Mice subjected to aP2-Cre mediated ablation of microsomal triglyceride transfer protein are resistant to high fat diet induced obesity
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چکیده
منابع مشابه
Mice subjected to aP2-Cre mediated ablation of microsomal triglyceride transfer protein are resistant to high fat diet induced obesity
BACKGROUND Microsomal triglyceride transfer protein (MTP) is essential for the assembly of lipoproteins. MTP has been shown on the surface of lipid droplets of adipocytes; however its function in adipose tissue is not well defined. We hypothesized that MTP may play critical role in adipose lipid droplet formation and expansion. METHODS Plasmids mediated overexpression and siRNA mediated knock...
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ژورنال
عنوان ژورنال: Nutrition & Metabolism
سال: 2016
ISSN: 1743-7075
DOI: 10.1186/s12986-016-0061-6